Tissue integration devices and methods of making the same
AssigneeProxy Biomedical Limited
InventorsTony Durkin, Dean King, Barry Nugent, Peter Mulrooney, Kieran Moloney, Peter H. Gingras
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Abstract
One aspect of the present disclosure relates to a tissue integration device. The tissue integration device can be produced by forming a polymer mixture into a shape. The polymer mixture can include a polymer resin and a growth-promoting medium. Next, at least one polymer forming the polymer resin can be oriented in at least one direction. The shaped polymeric material can then be formed into the tissue integration device.
Claims21
1-20. (canceled)
A method of making a tissue integration device comprising:
- forming a polymer mixture into a shape, the polymer mixture comprising a polymer resin and a growth-promoting medium;
- orienting at least one polymer comprising the polymer resin in at least one direction;
- and
- forming the shaped polymeric material into the tissue integration device.
The method of 21, wherein forming the shaped polymer material comprises stretching the shaped polymer material biaxially.
The method of 21, further comprising annealing the shaped polymer mixture to a specific target percentage after the orienting step.
A method of making a tissue integration device comprising:
- forming a polymer mixture into a shape, the polymer mixture comprising a polymer resin and a growth-promoting medium;
- orienting at least one polymer comprising the polymer resin in at least one direction;
- forming the shaped polymer mixture into the tissue integration device;
- and
- forming one or more line-of-sight pores in the tissue integration device, wherein the one or more line-of-sight pores are sized and dimensioned to promote tissue ingrowth when the tissue integration device is implanted in a subject.
A method for forming a tissue integration device, comprising:
- forming a polymer mixture that includes a polymer resin and a tissue growth-promoting medium;
- processing the polymer mixture into a shape selected from the group consisting of a plaque, a sheet, a film and a strip;
- orienting at least one polymer comprising the polymer resin in at least one direction;
- annealing the shaped polymer mixture;
- cutting the annealed, shaped polymer mixture into at least one strip;
- wrapping the at least one strip around a mandrel to form a tube of concentric annular layers;
- compressing the layers together to laminate the layers to form a tissue integration device;
- and
Dependencies are inferred from the claim text.