Methods for Cancer Detection with Quantum Dots

A method for cancer detection, wherein the method comprises the steps of:

• a) contacting conjugated quantum dots to tissue, wherein each of said conjugated quantum dots comprises a quantum dot conjugated to a biomarker specific moiety selected from anti-VEGF antibodies, anti-Tn antigen antibodies, anti-T antigen antibodies, anti-sial-T antigen antibodies, anti-sial-Tn antigen antibodies, anti-HER2 antibodies and anti-IGFR antibodies, for a time sufficient to bind at least some of said conjugated quantum dots to a biomarker on the tissue;
• b) removing unbound conjugated quantum dots from the tissue,
• c) exciting said bound conjugated quantum dots with excitation energy, and
• d) analyzing an emission from the bound conjugated quantum dots to detect presence of cancer.