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US 2020/0138981 A1Published application
Biomedical materials
AssigneesApaTech Limited, The University Court of the University of Aberdeen
InventorsIain Ronald Gibson, Janet Mabel Scott Skakle, Nigel Smith, Thomas Buckland
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Abstract
A synthetic calcium phosphate-based biomedical material comprising gadolinium. The material may comprises a compound having the general chemical formula: Ca10−yGdy(PO4)6−x(SiO4)x(OH)2−x+y where 0<x<1.3 and 0<y<1.3.
Claims21
A process for the synthesis of a calcium phosphate-based material comprising gadolinium and silicon, the process comprising:
- providing calcium or a calcium-containing compound, a gadolinium-containing compound, a phosphorus-containing compound and a silicon-containing compound;
- and
- forming a precipitate by reacting the compounds in an aqueous phase at an alkali pH;
- thereby synthesizing a calcium phosphate-based material comprising gadolinium, wherein at least some of the gadolinium is in the form of Gd3+ ions substituted in the calcium phosphate lattice, and wherein the material comprises a compound having the general chemical formula:
- Ca10−yGdy(PO4)6−x(SiO4)x(OH)2−x+y
- wherein 0.5<x<1.1 and 0<y<1.3.
3 more elements
Dependencies are inferred from the claim text.