US 2020/0138940 A1Published application

Stabilized pre-fusion rsv f proteins

AssigneeJanssen Vaccines & Prevention B.V.

InventorJohannes Petrus Maria LANGEDIJK

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Abstract

Stable pre-fusion respiratory syncitial virus (RSV) F proteins, immunogenic compositions including the proteins and uses thereof for the prevention and/or treatment of RSV infection are described.

Claims19

Dependent claims

A recombinant pre-fusion respiratory syncitial virus (RSV) Fusion (F) protein comprising a mutation of the amino acid residue at position 215, a mutation of the amino acid residue at position 357, and a mutation of the amino acid residue at position 371.

Dependencies are inferred from the claim text.

Facts

Application: 16/305,169Filed 29 May 2017
Priority: EP 16172008.130 May 2016
Published: 7 May 2020
Term ends: Not estimatedThe source records don’t support an estimate.

Classification14 codes

A61K 39/155
Viral antigens: paramyxoviridae, e.g. parainfluenza virus
C07K 14/005
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof: from viruses
A61K 39/12
Medicinal preparations containing antigens or antibodies: viral antigens
A61P 31/14
Antivirals: for RNA viruses

Family

US 10,953,087 B2Related patent
US 2020/0138940 A1This patent

From the US filing history. Foreign family members aren’t listed.

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