Machine learning systems and techniques for multispectral amputation site analysis
AssigneeSpectral Md, Inc.
InventorsWensheng Fan, John Michael DiMaio, Jeffrey Thatcher
Life of this patent
Estimating the term…
Abstract
Certain aspects relate to apparatuses and techniques for non-invasive and non-contact optical imaging that acquires a plurality of images corresponding to both different times and different frequencies. Additionally, alternatives described herein are used with a variety of tissue classification applications including assessing the presence and severity of tissue conditions, such as necrosis and small vessel disease, at a potential or determined amputation site.
Claims23
(canceled)
A tissue classification system comprising:
- at least one light emitter configured to emit light at each of a plurality of wavelengths to illuminate a tissue region, each of the at least one light emitter being configured to emit spatially-even light;
- at least one light detection element configured to collect the light after being emitted from the at least one light emitter and reflected from the tissue region;
- one or more processors in communication with the at least one light emitter and the at least one light detection element and configured to:
- identify at least one patient health metric value corresponding to a patient having the tissue region,
- use the at least one patient health metric value to select a classifier from among a plurality of classifiers, each of the plurality of classifiers trained from a different subset of a set of training data, wherein the classifier is selected based on having been trained with a subset of the set of the training data including data from other patients having the at least one patient health metric value;
- control the at least one light emitter to sequentially emit each of the plurality of wavelengths of light;
- receive a plurality of signals from the at least one light detection element, a first subset of the plurality of signals representing light emitted at the plurality of wavelengths and reflected from the tissue region;
- generate, based on at least some of the plurality of signals, an image having a plurality of pixels depicting the tissue region;
- for each pixel of the plurality of pixels depicting the tissue region:
- determine, based on the first subset of the plurality of signals, a reflectance intensity value at the pixel at each of the plurality of wavelengths, and
- determine a healing classification score of the pixel by inputting the reflectance intensity value into the classifier;
- and
- generate, based on the healing classification score of each pixel, an overall healing score for the plurality of pixels depicting the tissue region.
A tissue classification method comprising:
- selecting, based on at least one patient health metric value, a classifier from among a plurality of classifiers, each of the plurality of classifiers trained from a different subset of a set of training data, wherein the classifier is selected based on having been trained with a subset of the set of the training data including data from other patients having the at least one patient health metric value;
- receiving a plurality of signals from at least one light detection element positioned to receive light reflected from a tissue region, a first subset of the plurality of signals representing light emitted at a plurality of wavelengths reflected from the tissue region;
- generating, based on at least a portion of the plurality of signals, an image having a plurality of pixels depicting the tissue region;
- for each pixel of the plurality of pixels depicting the tissue region:
- determining, based on the first subset of the plurality of signals, a reflectance intensity value at the pixel at each of the plurality of wavelengths, and
- determining a healing classification score of the pixel by inputting the reflectance intensity value into the classifier;
- and
- generating, based on the healing classification score of each pixel, an overall healing score for the plurality of pixels depicting the tissue region.
16-18. (canceled)
A method of identifying a recommended location of an amputation, the method comprising:
- selecting a patient having a tissue region in need of amputation;
- programmatically controlling, via one or more hardware processors, an imaging system to capture data representing a plurality of images of the tissue region, the data representing the plurality of images including a first subset each captured using light of a different one of a number of different wavelengths reflected from the tissue region;
- generating, based on at least one of the plurality of images, an image having a plurality of pixels depicting the tissue region;
- for each pixel of the plurality of pixels depicting the tissue region:
- determining, based on the first subset of the data representing the plurality of images, a reflectance intensity value at the pixel at each of the plurality of wavelengths, and
- determining a healing classification score of the pixel by at least inputting the reflectance intensity value into a classifier;
- and
- identifying, based on the healing classification score of each pixel, the recommended location of the amputation within the tissue region.
25-27. (canceled)
Dependencies are inferred from the claim text.