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US 2020/0138312 A1Published application
Nanopatterned surface modifications on implantable medical device
AssigneeCase Western Reserve University
InventorsEvon Ereifej, Pamela Vandevord, Jeffrey R. Capadona
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Abstract
The present disclosure relates to an implantable medical device with surface modifications to add additional surface area to the surface of the implantable device. The surface modifications create a rough, nanopatterned surface of the implantable medical device. The rough, nanopatterned surface can mimic a natural environment of an area of the subject's body, thereby reducing an immune foreign body response.
Claims20
A method for manufacturing a medical device, the method comprising:
- providing a medical device, wherein the medical device comprises a smooth surface configured to interface with an area of a subject's body;
- and
- modifying the smooth surface of the medical device to have a rough, nanopatterned surface with increased surface area.
A method comprising:
- implanting a medical device into an area of a subject's body,
- wherein the medical device comprises a three-dimensional structure with a rough surface configured to interface with the area of the subject's body;
- and
- wherein the rough surface reduces an immune foreign body response to the medical device.
1 more element
A medical device comprising:
- a three-dimensional structure configured for implantation into an area of a subject's body,
- wherein the three-dimensional structure comprises a rough, nanopatterned surface configured to interface with the area of the subject's body,
- wherein the rough, nanopatterned surface mimics a natural environment of the area of the subject's body.
Dependencies are inferred from the claim text.