Forms of (R)-N-(4-chlorophenyl)-2-(cis-4-(6-fluoroquinolin-4-yl)cyclohexyl)propanamide
AssigneeShenzhen Rentai Pharmatech Ltd.
InventorsDongxu YI, Guobin REN, Jian MA, Shuhao WEN, Peiyu ZHANG, Yang LIU, Xuekun SHI, Jiajun HUANG, Yanqi ZHANG, Shigang RUAN, Mingjun YANG, Guangxu SUN
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Abstract
Forms B and C of (R)—N-(4-chlorophenyl)-2-(cis-4-(6-fluoroquinolin-4-yl)cyclohexyl)propanamide are stable under the conditions of light, high temperature and high humidity.
Claims17
Crystalline form or monohydrate or crystalline monohydrate of (R)—N-(4-chlorophenyl)-2-(cis-4-(6-fluoroquinolin-4-yl)cyclohexyl)propanamide.
The pharmaceutical composition according to claim 41, wherein the pharmaceutical composition is of an oral formulation, and preferably is a tablet.
Form B of crystalline monohydrate (R)—N-(4-chlorophenyl)-2-(cis-4-(6-fluoroquinolin-4-yl)cyclohexyl)propanamide.
Form C of (R)—N-(4-chlorophenyl)-2-(cis-4-(6-fluoroquinolin-4-yl)cyclohexyl)propanamide.
Dependencies are inferred from the claim text.