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US 2019/0381165 A1Published application
Vaccines and Diagnostics for Novel Porcine Orthoreoviruses
AssigneeVirginai Tech Intellectual Properties, Inc.
InventorsXiang-Jin Meng, Dianjun Cao, Athmaran Narayanappa, Elankumaran Subbiah
Life of this patent
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Abstract
Provided herein are diagnostics and vaccines to identify control and prevent novel porcine orthoreovirus type 3 (POV3) isolated from diarrheic feces of piglets from outbreaks in three states and ring-dried swine blood meal from multiple sources.
Claims20
A vaccine for protecting swine against porcine orthoreovirus type 3 (POV-3), comprising:
- an attenuated or killed POV-3, the POV-3 having a σ1 capsid protein with at least 98% sequence homology to the σ1 capsid protein represented by SEQ ID NO:
- 20;
- and
- a physiologically acceptable carrier, an adjuvant, or both.
1 more element
A method for making an antigen, comprising:
- propagating a POV-3 having a σ1 capsid protein with at least 98% sequence homology to the σ1 capsid protein represented by SEQ ID NO:
- 20 in a cell culture, in an embryonated chicken egg, or both.
Dependencies are inferred from the claim text.