Systems and methods for predicting adverse events and assessing level of sedation during medical procedures

A system for guiding procedural sedation, comprising at least one processor configured to:

• identify sedation agent information including at least one of a time, a type, and an amount of sedation agent administered to a patient;
• compute, using a pharmacokinetic model, a concentration of sedation agent in the body of the patient based on the sedation agent information;
• compute a first predicted sedation level based on the computed concentration;
• select a candidate dose of sedation agent based on the sedation agent information;
• compute a second predicted sedation level based on the candidate dose of sedation agent;
• and
• provide to a display, at least one of the computed concentration and the first predicted sedation level and at least one of the candidate dose of sedation agent and the second predicted sedation level.

A method for automatically guiding procedural sedation, comprising:

• identifying sedation agent information including at least one of a time, a type, and an amount of sedation agent administered to a patient;
• computing, using a pharmacokinetic model, a concentration of sedation agent in the body of the patient based on the sedation agent information;
• computing a first predicted sedation level based on the computed concentration;
• selecting a candidate dose of sedation agent based on the sedation agent information;
• computing a second predicted sedation level based on the candidate dose of sedation agent;
• and
• providing, to a display, at least one of the computed concentration and the first predicted sedation level and at least one of the candidate dose of sedation agent and the second predicted sedation level.