Systems and methods for identifying optimized ablation targets for treating and preventing arrhythmias sustained by reentrant circuit

A method for identifying optimized regions of interest, the method comprising:

• receiving at least one mesh generated from one or more images of a patient's heart;
• receiving activation data generated from one or more simulations of electrical-signal propagation over the mesh, the simulations being consistent with one or more heart conditions;
• generating at least one flow graph based on the activation data and the mesh, the flow graph comprising one or more nodes associated one or more elements and one or more edges connecting two or more nodes;
• designating a first set of one or more nodes as source nodes;
• designating a second set of one or more nodes as sink nodes;
• determining one or more flow graph segments connecting a source node to a sink node;
• determining one or more regions of interest, which correspond to a minimum number of cuts in the flow graph and a maximum flow through the flow graph.

A system for identifying optimized regions of interest, the system comprising:

• at least one non-transitory computer-readable medium configured to store instructions;
• and
• at least one processor configured to execute the instructions to perform operations comprising:
• receiving at least one mesh generated from one or more images of a patient's heart;
• receiving activation data generated from one or more simulations of electrical-signal propagation over the mesh, the simulations being consistent with one or more heart conditions;
• generating at least one flow graph based on the activation data and the mesh, the flow graph comprising one or more nodes associated one or more elements and one or more edges connecting two or more nodes;
• designating a first set of one or more nodes as source nodes;
• designating a second set of one or more nodes as sink nodes;
• determining one or more flow graph segments connecting a source node to a sink node;
• determining one or more regions of interest, which correspond to a minimum number of cuts in the flow graph and a maximum flow through the flow graph.

A non-transitory computer-readable medium storing a set of instructions that are executable by one or more processors to cause the processors to perform a method for identifying optimized regions of interest, the method comprising:

• receiving at least one mesh generated from one or more images of a patient's heart;
• receiving activation data generated from one or more simulations of electrical-signal propagation over the mesh, the simulations being consistent with one or more heart conditions;
• generating at least one flow graph based on the activation data and the mesh, the flow graph comprising one or more nodes associated one or more elements and one or more edges connecting two or more nodes;
• designating a first set of one or more nodes as source nodes;
• designating a second set of one or more nodes as sink nodes;
• determining one or more flow graph segments connecting a source node to a sink node;
• determining one or more regions of interest, which correspond to a minimum number of cuts in the flow graph and a maximum flow through the flow graph.