Nucleic acid sequencing device containing graphene

Abstract

In various aspects of the present disclosure, a sequencing device structure is disclosed. The device structure has an array of metallic conducting electrode pairs, each electrode pair defining a bridging source and drain arrangement separated by a nanogap, the electrode pairs deposited and patterned on a dielectric substrate; a graphene layer deposited onto each electrode pair bridging the source and drain electrodes in each pair, wherein each electrode pair is in electrical isolation from each other; and a dielectric masking layer contacting the graphene layer, the masking layer having an opening exposing a portion of the graphene layer directly over each nanogap, wherein each opening is dimensioned in size to accommodate at least one polymerase enzyme molecule. The graphene layer may include defective graphene.

Dependencies are inferred from the claim text.