Systems and methods for imaging microwell plate samples

A system for analyzing one or more samples, the system comprising:

• a microwell plate including a plurality of rows of wells configured to store samples;
• a sensor array that is moveable relative to the microwell plate along a first axis between a first position and a second position to allow a portion of the sensor array to be disposed within a first one of the plurality of rows of wells when the sensor array is in the second position;
• an objective;
• and
• one or more linear translation stages configured to move the microwell plate relative to the objective (i) along a second axis that is orthogonal to the first axis, (ii) along a third axis that is orthogonal to the first axis and the second axis, or (iii) both (i) and (ii).

A method for imaging one or more liquid samples disposed in a microwell plate, the method comprising:

• moving a sensor array including a plurality of sensors from a first vertical position towards a second vertical position such that each of the plurality of sensors is disposed within a corresponding well in a first row of wells of the microwell plate;
• moving, using one or more linear translation stages, the microwell plate such that a first one of the plurality of sensors is positioned within a field of view of an objective;
• generating, using the objective and an imaging device, first image data reproducible as one or more images of the first sensor;
• moving, using the one or more linear translation stages, the microwell plate such that a second one of the plurality of sensors is positioned within the field of view of the objective;
• and
• generating, using the objective and the imaging device, second image data reproducible as one or more images of the second sensor.