Loading patent…
AssigneeKoninklijke Philips N.V.
InventorsAnja VAN DE STOLPE, Rick VELTER, Wilhelmus Franciscus Johannes VERHAEGH, Hendrik Jan VAN OOIJEN, Martijn Theodorus Lambert AKSE
Estimating the term…
The present invention relates to certain target genes of the FOXO transcription factor family, which are markers for an oxidative stress state and can be used for inferring an oxidative stress state of a FOXO transcription factor element in the body of a medical subject. The invention further relates to methods for inferring an oxidative stress state of a FOXO transcription element and for inferring the activity of the FOXO/PI3K cellular signalling pathway based on expression levels of the target genes as well as products to perform the methods.
Method for inferring the activity of a PI3K cellular signaling pathway in a subject based at least on the oxidative stress state of the subject, preferably the oxidative stress state of a FOXO transcription factor element in the subject, comprising,
Dependencies are inferred from the claim text.