US 2019/0376090 A1Published application

RNA-Guided Targeting of Genetic and Epigenomic Regulatory Proteins to Specific Genomic Loci

AssigneeThe General Hospital Corporation

InventorsJ. Keith Joung, Morgan Maeder

Life of this patent

Estimating the term…

Abstract

Methods and constructs for RNA-guided targeting of heterologous functional domains such as transcriptional activators to specific genomic loci.

Claims25

Dependent claims

A fusion protein comprising catalytically inactive CRISPR associated 9 (dCas9) protein linked to a heterologous functional domain.

Dependencies are inferred from the claim text.

Facts

Application: 16/535,199Filed 8 Aug 2019
Priority: 15 Mar 2013
Published: 12 Dec 2019
Term ends: Not estimatedThe source records don’t support an estimate.

Classification29 codes

C12N 15/907
Using homologous recombination: in mammalian cells
C07K 14/005
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof: from viruses
C07K 14/195
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof: from bacteria
C12N 9/0071
Oxidoreductases: acting on paired donors with incorporation of molecular oxygen

Family

Application61/799,647Us provisional application · filed 15 Mar 2013
Application61/838,178Us provisional application · filed 21 Jun 2013
Application61/838,148Us provisional application · filed 21 Jun 2013
Application61/921,007Us provisional application · filed 26 Dec 2013
Application14/775,869Continuation · filed 14 Sep 2015
Application16/535,199Continuation
US 10,378,027 B2Related patent
US 11,168,338 B2Related patent
US 2016/0010076 A1Published application
US 2019/0376090 A1This patent

From the US filing history. Foreign family members aren’t listed.

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