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US 2019/0376056 A1Published application
Nanostructure for detecting cell-free dna using conductive polymer and the use thereof
AssigneeNational Cancer Center
InventorsYoungnam CHO, Eun Sook LEE
Life of this patent
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Abstract
Disclosed is a structure for detecting cell-free DNA using a conductive polymer and the use thereof. More particularly, a nanostructure composed of a surface-modified conductive polymer for isolating and detecting cell-free DNA is disclosed. By using the nanostructure, cell-free DNA including circulating tumor DNA, etc. can be effectively detected and isolated.
Claims8
-8. (canceled)
A method of detecting and isolating cell-free DNA (cfDNA), the method comprising:
- positively charging a surface of a conductive polymer forming a nanostructure;
- treating the conductive polymer with a biological substance to attach the cfDNA to the conductive polymer;
- and
- capturing the cfDNA with the conductive polymer or releasing the cfDNA from the conductive polymer by applying an electric signal.
1 more element
-20. (canceled)
Dependencies are inferred from the claim text.