Granulocytic myeloid-derived suppressor cells (GR-MDSC) accumulate in human breastmilk
AssigneeEberhard Karls Universitaet Tuebingen Medizinische Fakultaet
InventorsNatascha Koestlin, Christian Gille
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Abstract
The present invention relates to myeloid-derived suppressor cells (MDSC) and exosomes derived therefrom (MDSC exo) and application thereof.
Claims15
A method of preparing myeloid-derived suppressor cells (MDSC) comprising a step of isolating MDSC from breast milk.
The method of claim 2, wherein the step of isolating MDSC from breast milk includes the following sub-steps:
- providing breast milk obtained from a breastfeeding female individual,
- centrifuging the breast milk to pelletize the milk cells,
- discarding the supernatant and washing the pelletized milk cells to obtain the MDSC.
A method of preparing myeloid-derived suppressor cells (MDSC) derived exosomes (MDSC exo) comprising a step of isolating MDSC exo from breast milk.
A method of treatment of a living being, comprising the administration of myeloid-derived suppressor cells (MDSC) or MDSC derived exosomes (MDSC exo) isolated from breast milk.
15-20. (canceled)
Dependencies are inferred from the claim text.