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AssigneeVanderbilt University
InventorsEva M. Harth, David J. Calkins, Alice E. Van Der Ende
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In one aspect, the invention relates to polymers, crosslinked polymers, functionalized polymers, nanoparticles, and functionalized nanoparticles and methods of making and using same. In one aspect, the invention relates to degradable polymers and degradable nanoparticles. In one aspect, the invention relates to methods of preparing degradable nanoparticles and, more specifically, methods of controlling particle size during the preparation of degradable nanoparticles. In one aspect, the degradable nanoparticles are useful for complexing, delivering, and releasing payloads, including pharmaceutically active payloads. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
A composition comprising a crosslinked degradable polyester particle including polymer backbones comprising δ-valerolactone monomers residues, the crosslinked degradable polyester particle produced by crosslinking a polymer comprising:
The composition of claim 2, further comprising:
A composition comprising a crosslinked degradable polyester particle including polyvalerolactone backbones polymerized from δ-valerolactone monomers.
Dependencies are inferred from the claim text.