Nanomaterial and method of production of a nanomaterial for medical applications, such as mri or sers
AssigneesUniversite Paris Nord, Centre National De La Recherche Scientifique
InventorJolanda SPADAVECCHIA
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Abstract
A method for producing nanomaterial product which comprises at least one hybrid nanoparticle Gold-metal-Polymer, the polymer comprising at least one biopolymer, the atoms of metal being linked with the atom of Gold, the metal being chosen among: Gd, Co, Eu, Tb, Ce, Mn, Fe, Zn, Cu, the method being realized in an aqueous solvent, without reactive or stabilizer agent, and presenting a step of reducing: tetrachloroauric acid (HAuCl4) and metal ions, in the presence of the biopolymer, the biopolymer being used as a stabilizer agent.
Claims14
A method for the synthesis of nanomaterial product which comprises at least one hybrid nanoparticle of gold-metal-biopolymer,
- the biopolymer comprising at least one biopolymer being chosen among:
- collagen, chitosan, polyethylene glycol diacid, alginate, or theirs derivatives,
- the metal being chosen among:
- Gd, Co, Eu, Tb, Ce, Mn, Fe, Zn, Cu,
- the method being realized in an aqueous solvent and presenting:
- Preparation steps (Ai-Aii, Bi-Bii) of mixing the gold ions, the metal ions and the biopolymer, for obtaining a resulting solution with gold-metal-biopolymer complex,
- One single step (Aiii, Biii) of synthesizing nanomaterial product which is the reduction of gold ions and metal ions in the presence of the biopolymer, by introducing a reducing agent in the resulting solution, the biopolymer being used as a stabilizer agent,
- the method being realized without chemical linker.
A nanomaterial product, comprising at least one hybrid nanoparticle of gold-metal-biopolymer, wherein:
- The metal is selected from:
- Gd, Co, Eu, Th, Ce, Mn, Fe, Zn, Cu,
- The biopolymer is selected from:
- collagen, chitosan, polyethylene glycol diacid, alginate, hydroxyapatite (HAPA), and theirs derivatives,
- the atom(s) of gold and the atoms of metal being linked by ionic bonds.
Dependencies are inferred from the claim text.