US 2019/0336568 A1 · ANTIMICOBIAL PEPTIDES FOR INHIBITING DRUG-RESISTANT BACTERIA AND USES THEREOF

Abstract

Disclosed are antimicrobial peptides capable of inhibiting and killing multiple drug-resistant bacteria, including XH-12C, XH-12B and XH-12A. The application further provides uses of the antimicrobial peptides in the preparation of a drug for inhibiting and/or killing fungi, Gram-positive bacteria, Gram-negative bacteria and drug-resistant bacteria and in the manufacture of medical carriers.

Claims13

Dependent claims

An antimicrobial peptide capable of inhibiting and killing multiple drug-resistant microorganisms, wherein the antimicrobial peptide is any one peptide selected from the group consisting of:

XH-12C:
Phe-Phe-Arg-Lys-Val-Leu-Lys-Leu-Ile-Arg-Lys-Ile-
Trp-Arg shown as SEQ ID NO. 1;
XH-12B:
Phe-Phe-Arg-Lys-Val-Leu-Lys-Leu-Ile-Arg-Lys-Ile-
Phe shown as SEQ ID NO. 2;
and
XH-12A:
Phe-Phe-Arg-Lys-Val-Leu-Lys-Leu-Ile-Arg-Lys-Ile
shown as SEQ ID NO. 3.

7 more elements

Dependencies are inferred from the claim text.

Facts

Application

16/407,132Filed 8 May 2019

Priority

CN 201610983926.69 Nov 2016

Published

7 Nov 2019

Term ends

Not estimatedThe source records don’t support an estimate.

Classification15 codes

A61K 38/10
Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof: peptides having 12 to 20 amino acids
A23K 20/147
Amino acids; Derivatives thereof: polymeric derivatives, e.g. peptides or proteins
A23L 33/18
Amino acids, peptides or proteins: peptides; Protein hydrolysates
A61P 31/04
Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics: antibacterial agents

Antimicobial peptides for inhibiting drug-resistant bacteria and uses thereof

Life of this patent

Antimicobial peptides for inhibiting drug-resistant bacteria and uses thereof

Life of this patent

Abstract

Claims13