Laser-assisted transdermal delivery of nanoparticulates and hydrogels
AssigneeInternational Business Machines Corporation
InventorsJerome M. Felsenstein, James L. Hedrick, James J. Wynne, Donna S. Zupanski-Nielsen
Life of this patent
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Abstract
A method for laser assisted delivery of therapeutic agents includes selectively controlling a valve connected to a first channel disposed within a first sidewall of a nozzle, applying, through the first channel, a first substance to penetrate dermis to a predetermined depth, and administering, through a second channel unconnected with the valve and disposed within a second sidewall of the nozzle, a second substance to remove debris.
Claims20
A method for laser assisted delivery of agents, comprising:
- selectively controlling a valve connected to a first channel disposed within a first sidewall of a nozzle;
- applying, through the first channel, a first substance to penetrate dermis to a predetermined depth;
- and
- administering, through a second channel unconnected with the valve and disposed within a second sidewall of the nozzle, a second substance to remove debris.
A method for laser assisted delivery of agents, comprising:
- emitting a laser beam to form an opening in epidermis to expose dermis;
- selectively controlling a valve connected to a first channel disposed within a first sidewall of a nozzle;
- applying, through the first channel, a first substance to penetrate the dermis to a predetermined depth;
- and
- administering, through a second channel unconnected with the valve and disposed within a second sidewall of the nozzle, a second substance to remove debris.
A method for laser assisted delivery of agents, comprising:
- selectively controlling a valve connected to a first channel disposed within a first sidewall of a nozzle;
- applying, through the first channel, a first substance to penetrate dermis to a predetermined depth;
- verifying the application of the first substance to the predetermined depth with a non-invasive optical imaging technology;
- and
- administering, through a second channel unconnected with the valve and disposed within a second sidewall of the nozzle, a second substance to remove debris.
Dependencies are inferred from the claim text.