Methods, compositions, and kits for detecting a cell in a sample

A method of detecting one or more bactericide or bacteriostatic agent resistant bacteria in a sample comprising:

• a) providing a first sample comprising one or more types of bacteriophages, wherein each of said one or more types of bacteriophages bind to one or more specific types of receptor of one or more types of said bacteria if present in said sample to form complexes of bacteria and bacteriophage;
• and wherein said one or more types of bacteriophages are incapable of replicating inside said one or more types of bacteria;
• b) providing a second sample suspected of comprising one or more types of said bacteria, wherein said one or more types of said bacteria are susceptible to infection by said one or more types of bacteriophage;
• c) contacting said first sample with said second sample to form a sample mixture, wherein said one or more types of bacteriophages if present in said first sample forms one or more complexes with said one or more types of bacteria in said sample mixture;
• d) incubating said sample mixture in a media comprising one or more bactericide or bacteriostatic agent;
• e) contacting one or more compounds to said media;
• f) measuring any change of said one or more compounds in said media;
• wherein any change of said one or more compounds is indicative of the presence or absence of one or more types of bacteriophage infected bacteria in said sample mixture, and wherein the presence or absence of one or more types of bacteriophage infected bacteria in said sample mixture is indicative of the presence or absence of one or more types of bactericide or bacteriostatic agent resistant bacteria in said second sample.