Silicone hydrogels comprising high levels of polyamides

A silicone hydrogel formed from a reactive monomer mixture comprising:

• a. At least one hydroxyalkyl (meth)acrylate;
• b. a hydroxyl-containing silicone component that comprises a mixture of a first hydroxyl substituted, linear poly(dialkylsiloxane) of Formula VI,
• wherein
• Z is selected from O, N, S or NCH2CH2O, when Z is O or S R2 is not present;
• R1 is independently H or methyl;
• R2 is H or is a linear, branched, or cyclic alkyl group containing one to eight carbon atoms, any of which may be further substituted with at least one hydroxy group, and which may be optionally substituted with amide, ether, and combinations thereof;
• R3 and R4 are independently a linear, branched, or cyclic alkyl group containing one to eight carbon atoms, any of which may be further substituted with at least one hydroxy group, amide, ether, and combinations thereof;
• R3 and R4 may be independently selected from methyl, ethyl or phenyl, or may be methyl;
• n is 4-8 for the first monofunctional hydroxyl substituted, poly(disubstituted siloxane), and,
• a second hydroxyl substituted, linear poly(dialkylsiloxane) that is
• a multifunctional hydroxyl substituted, linear poly(dialkylsiloxane) of Formula XI having 10 to 500, or 10 to 200, or 10 to 100 siloxane repeating units,
• Wherein R1 is independently a hydrogen atom or methyl group;
• R15 and R16 are independently a linear, branched, or cyclic alkyl group containing one to eight carbon atoms, any of which may be further substituted with at least one hydroxy group, amido, ether, amino, carboxyl, carbonyl groups and combinations thereof;
• or are independently methyl or ethyl;
• and
• n is 10 to 200;
• 10 to 100;
• 10 to 50;
• 10 to 20;
• wherein a ratio of the second hydroxyl substituted, linear poly(dialkylsiloxane) to the first hydroxyl substituted, linear poly(dialkylsiloxane) is in a range of 0.1 to 1.3, or 0.4 to 1;
• greater than 15 weight percent, based on the total weight of the reactive monomer mixture, of at least one polyamide selected from the group consisting of PVP, PVMA, PDMA, PNVA, polyacrylamide, and copolymers and mixtures thereof;
• and
• optionally, methacrylic acid.

A silicone hydrogel formed from a reactive monomer mixture comprising:

• a. between 15 and about 40 wt % at least one polyamide;
• b. at least one hydroxyl silicone-containing monomer;
• c. at least one hydroxyl substituted poly(disubstituted siloxane) selected from the group consisting of poly(disubstituted siloxane) having 4 to 8 siloxane repeating units, and multifunctional hydroxyl substituted poly(disubstituted siloxane)s having 10 to 200 siloxane repeating units, and mixtures thereof;
• d. at least one hydrophilic monomer.