Anti-c-met antibodies and uses thereof
AssigneeViroMed Co., Ltd.
InventorsSeung Shin YU, Jae-Gyun JEONG, Dongsik KIM, Juwon SHIM
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Abstract
The present disclosure provides a pharmaceutical composition for preventing or treating a variety of diseases through c-Met activation in cells induced by the anti-c-Met antibody described herein which functions as a c-Met agonist. The current invention concerns a method for preventing or treating various diseases through c-Met activation by the anti-c-Met antibody described herein.
Claims26
A method for treating a disease selected from the group consisting of ischemic disorder, stroke, kidney injury or disease, retinal neovascularization disorder, neurological disorder or disease, and wound healing, the method comprising administering to a subject in need thereof a therapeutically effective amount of a polypeptide or a pharmaceutical composition comprising the polypeptide, wherein the polypeptide comprises an immunoglobulin heavy chain variable domain which comprises a CDR1 of SEQ ID NO:5, a CDR2 of SEQ ID NO:6, a CDR3 of SEQ ID NO:7 and a light chain variable domain which comprises a CDR1 of SEQ ID NO:8, a CDR2 of SEQ ID NO:9 and a CDR3 of SEQ ID NO:10.
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Dependencies are inferred from the claim text.