US 2019/0315807 A1 · VIRUS-LIKE PARTICLES WITH HIGH-DENSITY COATING FOR INDUCING THE EXPRESSION OF ANTIBODIES

Abstract

The invention relates to a fusion protein comprising a polypeptide of interest, a transmembrane domain and an HIV gag polypeptide, or their functionally equivalent variants. The invention also relates to the polynucleotides, vectors, host cells and virus-like particles expressing or presenting said fusion proteins and to the pharmaceutical, immunogenic or vaccines composition containing said fusion proteins, polynucleotides, vectors, host cells and virus-like particles and their use in human and veterinary medicine.

Claims24

Dependent claims

A fusion protein which comprises from the N- to the C-terminus:

(a) a polypeptide of interest, or a functionally equivalent variant thereof,
(b) a transmembrane domain, or a functionally equivalent variant thereof, and
(c) an HIV gag polypeptide, or a functionally equivalent variant thereof.

Dependencies are inferred from the claim text.

Facts

Application

16/321,271Filed 26 Jul 2017

Priority

EP EP16382364.427 Jul 2016

Published

17 Oct 2019

Term ends

Not estimatedThe source records don’t support an estimate.

Classification26 codes

A61K 39/12
Medicinal preparations containing antigens or antibodies: viral antigens
C07K 14/005
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof: from viruses
A61K 39/21
Viral antigens: retroviridae, e.g. equine infectious anemia virus
A61P 31/18
For RNA viruses: for HIV

Virus-like particles with high-density coating for inducing the expression of antibodies

Life of this patent

Virus-like particles with high-density coating for inducing the expression of antibodies

Life of this patent

Abstract

Claims24