Glucose uptake inhibitors

A compound having the formula I:

• or a pharmaceutically acceptable salt thereof,
• wherein:
• A is a group having the formula:
• Ring B is a five- or six-membered ring containing 1 or 2 heteroatoms selected from the group consisting of N, O and S;
• Ring C is a five- or six-membered aryl or heteroaryl ring containing from 0 to 2 heteroatoms selected from the group consisting of N, O and S;
• each R1 is independently selected from the group consisting of halo, C1-C6 alkyl, C2-C6 alkenyl, C1-C6 alkoxy, C3-C6 cycloalkyl, oxo, hydroxy, amino, cyano and C1-C3 perfluoro alkyl;
• n is selected from 0, 1, or 2;
• each R2 is independently selected from the group consisting of halo, C1-C6 alkyl, C2-C6 alkenyl, C1-C6 alkoxy, C3-C6 cycloalkyl, oxo, hydroxy, amino, cyano and C1-C3 perfluoro alkyl;
• m is selected from 0, 1, or 2;
• R3 and R4 are H;
• D is selected from the group consisting of —O—(CH2)y—C(═O)NR5R6, —O—C(═O)—(CH2)y—NR5R6, —O—(CH2)y—NR5R6, —NH—C(═O)—(CH2)y—NR5R6, —NH—C(═O)—(CH2)y—R7, and —NH—(CH2)y—NR5R6;
• y is selected from 1, 2, or 3;
• R5 and R6 are independently selected from the group consisting of H, C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, —(C1-C6 alkyl)-O—(C1-C6 alkyl), aryl, aralkyl, heteroaryl, and C3-C6 cycloalkyl,
• or R5 and R6 may be taken together with the nitrogen to which they are attached to form a 5- to 6-membered heterocyclic ring having up to 3 heteroatoms selected from N, O, and S, and which is optionally substituted by from 1 to 3 substituents independently selected from halo, C1-C6 alkyl, C2-C6 alkenyl, C1-C6 alkoxy, C3-C6 cycloalkyl, oxo, hydroxy, amino, cyano and C1-C3 perfluoro alkyl;
• and
• R7 is selected from the group consisting of aryl, heteroaryl, and a hetercyclic group.