Meglumine salts of thienopyrimidines

A method of treating or preventing a cardiovascular disease or condition in a mammal in need thereof comprising administering to the mammal a therapeutically effective amount of a salt of a compound according to Formula (I):

• or stereoisomers, tautomers or hydrates thereof,
• wherein:
• R1 is hydrogen, (C1-C6)alkyl, (C1-C6)alkoxy or (C1-C6)haloalkyl containing 1-6 halogen atoms;
• R2 is hydrogen, (C1-C6)alkyl, [(C1-C6)alkylene]aryl or amino;
• R3 is hydrogen, (C1-C6)alkyl, (C2-C6)alkenyl, [(C1-C6)alkylene]N(R4)(R5), [(C1-C6)alkylene]S(R4) or —X—Y, or R2 and R3 together with the atoms to which they are attached form a heterocyclyl;
• R4 and R5 are independently H or (C1-C6)alkyl;
• X is a chemical bond, —CH2—, —CH(OH)—, —CH(C6H5)—, —CO—, —CH2CH2—, CH2CO—, —COCH2—, S, O or NH;
• Y is cycloalkyl, heterocyclyl, aryl or heteroaryl;
• Z is S or O;
• n is 0, 1, 2, 3 or 4;
• M+ is
• and
• wherein any alkyl, alkylene, cycloalkyl, heterocyclyl, heteroaryl or aryl is optionally substituted with 1, 2 or 3 groups selected from OH, CN, halogen, (C1-C6)alkyl, O(C1-C6)alkyl, (C2-C6)alkenyl, haloalkyl, amino, oxo and nitro.