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US 2019/0315697 A1Published application
Isotopologues of 2-(tert-butylamino)-4-((1r,3r,4r)-3-hydroxy-4-methylcyclohexylamino)-pyrimidine-5-carboxamide
AssigneeSignal Pharmaceuticals, LLC
InventorsHon-Wah MAN, Mohit Atul KOTHARE
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Abstract
Provided herein are isotopologues of Compound A, which are enriched with isotopes such as, for example, deuterium. Pharmaceutical compositions comprising the isotope-enriched compounds, and methods of using such compounds are also provided.
Claims7
A compound, wherein the compound is a compound having the following structure:
- or a pharmaceutically acceptable salt, stereoisomer or solvate thereof,
- wherein one or more of Y1, Y2, Y3, Y4, Y5, Y6, Y7, Y8, Y9, Y10, Y11, Y12, Y13, Y14, Y15, Y16, Y17, Y18, Y19, Y20, Y21, and Y22 is a hydrogen that is isotopically enriched with deuterium, and the others of Y1, Y2, Y3, Y4, Y5, Y6, Y7, Y8, Y9, Y10, Y11, Y12, Y13, Y14, Y15, Y16, Y17, Y18, Y19, Y20, Y21, and Y22 are non-enriched hydrogen atoms.
Dependencies are inferred from the claim text.