Antagonists of human integrin (alpha4)(beta7)

A compound represented by formula (I):

• wherein:
• R1 is H, alkyl, alkylene-cycloalkyl, heterocyclyl, alkylene-O-alkyl, aryl, heteroaryl, or alkylene-CF3;
• R2 is heterocyclyl;
• R3 is, or;
• R4 is H, or (C1-C6)-alkyl;
• Ra is H, alkyl, cycloalkyl, CN, or —O-alkyl;
• Rb is H, alkyl, aryl, heteroaryl, heterocylcyl, —O-cycloalkyl, —O-aryl, or —O— heterocyclyl;
• Rc is H, alkyl, cycloalkyl, hetrocyclyl, or alkylene-CF3;
• Rd is aryl, heteroaryl, heterocyclyl, —O-cycloalkyl, —O-aryl, or —O-heterocyclyl;
• and
• Re is aryl, heteroaryl, or heterocyclyl;
• or a pharmaceutically acceptable salt thereof.