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US 2019/0315679 A1Published application
Solid forms of an adamantyl compound, compositions and uses thereof
AssigneeNorth & South Brother Pharmacy Investment Company Limited
InventorsHuiqing Ye, Jinchao Xu, Bifei He, Guangyuan Liu, Yuping Fan, Zhongqing Wang, Zhonhhua Luo
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Abstract
Provided herein are crystalline forms of (((((1r, 3R, 5S, 7r)-3, 5-dimethyladamantan-1-yl)carbamoyl) oxy) methyl benzoate (Compound (I)): Also provided are compositions comprising the crystalline forms of Compound (I), processes of manufacture and methods of using the crystalline forms of Compound (I).
Claims25
A crystalline form of Compound (I)
- selected from
- crystalline Form I characterized by an X-ray powder diffraction pattern comprising at least three peaks selected from the peaks expressed as 2θ at 7.7±0.2°, 8.9±0.2°, 10.7±0.2°, 13.1±0.2°, 14.2±0.2°, 15.4±0.2°, 18.0±0.2°, 18.7±0.2°, 21.4±0.2°, 21.6±0.2°, 22.4±0.2°, 22.8±0.2°, 23.9±0.2°, 25.5±0.2°, 26.5±0.2°, and 27.0±0.2°, or
- crystalline Form II characterized by an X-ray powder diffraction pattern comprising at least three peaks selected from the peaks expressed as 2θ at 9.6±0.20, 13.8±0.2°, 14.7±0.2°, 15.0±0.2°, 16.1±0.2°, 16.8±0.2°, 17.8±0.2°, 18.5±0.2°, 19.0±0.2°, 19.4±0.2°, 20.4±0.2°, 21.7±0.2° and 22.6±0.2°.
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Dependencies are inferred from the claim text.