Chromatography and synthesis column apparatus and method of assembly
AssigneeAsahi Kasei Bioprocess America, Inc.
InventorMichael D. Brandt
Life of this patent
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Abstract
Chromatography and synthesis columns, assemblies, components, and methods of assembly and disassembly are disclosed including a support assembly having lifting mechanisms in each of the legs to raise and lower a frame secured to the column, a swing arm and/or carriage guiding movement of a bottom plate of the column, a bolt-free coupling between the main tube and bottom plate of the column, and upper and lower slurry ports in the main tube of the column.
Claims32
A base assembly for a chromatography column having a main tube and a bottom plate, the base assembly comprising:
- a frame secured to the main tube of the chromatography column;
- legs mounted to the frame to support the chromatography column in an upright orientation;
- and
- lifting mechanisms of each of the legs configured to raise and lower the frame.
A base assembly for a chromatography column having a main tube and a bottom plate, the base assembly comprising:
- a frame secured to the main tube of the chromatography column;
- legs mounted to the frame to support the chromatography column in an upright orientation;
- a rigid swing arm having a proximal end mounted to one of the legs and a distal end mounted to the bottom plate, the swing arm configured to guide pivoting of the bottom plate along a horizontal plane, and
- wherein the one of the legs is spaced from at least another one of the legs a distance sized so that the bottom plate can be pivoted therebetween along a radius of the swing arm.
A method of servicing a chromatography column having a main tube and a bottom plate and supported by a base assembly having a frame mounted to the main tube and legs mounted to the frame, the method comprising:
- uncoupling the bottom plate from the main tube;
- operating lifting mechanisms of each of the legs to raise the frame and the main tube;
- and
- moving the bottom plate out from underneath the main tube.
Dependencies are inferred from the claim text.