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AssigneeUniversity of Pittsburgh—Of the Commonwealth System of Higher Education
InventorsStephen Weber, Stephen Robert Groskreutz, Anthony Robert Horner, Rachael-Anh Elizabeth Wilson
Estimating the term…
A method comprising: introducing a sample volume into an inlet end of a liquid chromatography column, wherein the liquid chromatography column includes a focusing segment proximal to the inlet end of the liquid chromatography column and a separation segment proximal to an elute outlet of the liquid chromatography column; maintaining only the focusing segment at a first temperature as the sample is introduced into the focusing segment; and subsequently heating the focusing segment to a second temperature that is higher than the first temperature after the entire sample volume has been introduced into the focusing segment.
A method comprising:
A device comprising:
A device comprising:
A method for modifying a liquid chromatography column comprising coupling to a sample inlet of the liquid chromatography column a precolumn having a longitudinal axial length and comprising a sample introduction inlet, an elute outlet, at least one longitudinally-extending focusing segment, and at least one Peltier thermoelectric cooling element aligned along the focusing segment, wherein the sample inlet of the liquid chromatography column is coupled to the elute outlet of the precolumn.
Dependencies are inferred from the claim text.