Deep Brain Stimulation Apparatus and Deep Brain Stimulation Method on Basis of Surface-Enhanced Raman Spectroscopy

A deep brain stimulation apparatus based on surface-enhanced Raman spectroscopy, the deep brain stimulation apparatus comprising:

• a stimulator configured to apply electrical stimulation to a brain;
• a light source configured to emit light to the brain;
• plasmonic nano-particles configured to allow surface-enhanced Raman scattering (SER) by contacting a neurotransmitter when the brain secretes the neurotransmitter as a result of the electrical stimulation;
• a photodetector configured to, when the light incident from the light source is scattered by the neurotransmitter in contact with the plasmonic nano-particles, detect scattered light through an optical fiber;
• a signal processing analyzer configured to convert a light signal from the photodetector into an electric signal;
• and
• a controller configured to receive an analysis signal of the signal processing analyzer to control the stimulator,
• wherein the plasmonic nano-particles are bonded to a surface of the optical fiber and inserted into a body together with the optical fiber.