Back to results
US 2019/0314383 A1Published application
Compositions for the treatment of hypertension
AssigneesThe George Institute for Global Health, The University of Sydney
InventorsAnthony RODGERS, Clara CHOW
Life of this patent
Estimating the term…
Abstract
Provided herein are pharmaceutical compositions that are useful for the treatment of hypertension comprising an angiotensin II receptor blocker, a diuretic, a calcium channel blocker, and a beta-blocker, wherein the dose of each component is below the lowest dose approved for the treatment of hypertension for the component.
Claims20
A pharmaceutical composition, comprising
- (a) irbesartan;
- (b) indapamide;
- (c) amlodipine besylate;
- and
- (d) bisoprolol fumarate;
- wherein the dose of irbesartan is about 30 mg to about 45 mg, the dose of indapamide is about 0.5 mg to about 0.75 mg, the dose of amlodipine besylate is about 1 mg to about 1.5 mg, and the dose of bisoprolol fumarate is about 2 mg to about 3 mg, and wherein (a), (b), (c) and (d) are provided in one formulation.
3 more elements
(canceled)
-8. (canceled)
-12. (canceled)
-16. (canceled)
-19. (canceled)
-26.
A method of treating hypertension in a subject in need thereof comprising administering the pharmaceutical composition, comprising.
- (a) irbesartan;
- (b) indapamide;
- (c) amlodipine besylate;
- and
- (d) bisoprolol fumarate;
- wherein the dose of irbesartan is about 30 mg to about 45 mg, the dose of indapamide is about 0.5 mg to about 0.75 mg, the dose of amlodipine besylate is about 1 mg to about 1.5 mg, and the dose of bisoprolol fumarate is about 2 mg to about 3 mg, and wherein (a), (b), (c) and (d) are provided in one formulation.
3 more elements
Dependencies are inferred from the claim text.