A method of operating a surgical stapling instrument including a body that supports a motor, a shaft assembly extending distally from the body, an end effector at a distal end of the shaft assembly, and a firing assembly having a translating member configured to translate through the end effector, wherein the end effector includes a jaw configured to receive a staple cartridge and an anvil pivotable relative to the jaw, wherein one of the jaw or the anvil includes an elongate slot, wherein the translating member includes a guide element slidably disposed within the elongate slot and a cutting element configured to cut tissue, wherein the translating member is configured to translate distally through the staple cartridge to thereby drive staples into tissue and cut the tissue with the cutting element, the method comprising:
- (a) receiving an unspent staple cartridge within the jaw, wherein the unspent staple cartridge includes a plurality of staples;
- (b) in response to a first user input, pivoting the anvil toward the unspent staple cartridge to thereby clamp tissue therebetween;
- (c) in response to a second user input, activating the motor to urge the translating member distally toward the unspent staple cartridge;
- and
- (d) engaging a first blocking feature of the translating member with a second blocking feature of the unspent staple cartridge to thereby inhibit distal translation of the translating member through the unspent staple cartridge.