Systems and methods for monitoring subjects for hereditary cancers

A non-transitory computer readable storage medium for determining whether a first human has an actionable risk for each of a plurality of hereditary cancers, the non-transitory computer readable storage medium storing instructions, which when executed by a device comprising one or more processors, cause the one or more processors to perform a method comprising:

• a) responsive to a request by a medical practitioner, obtaining an electronic medical record associated with the first human, via a computer system having a processor programmed to receive medical records, the electronic medical record of the first human comprising a plurality of data items, wherein the plurality of data items includes:
• an age of the first human,
• whether the first human has been diagnosed with a cancer, and
• an indication of whether a second human has been afflicted with a cancer,
• wherein the second human shares a first degree, second degree, or third degree consanguineous relationship with the first human;
• b) for each respective hereditary cancer in the plurality of hereditary cancers, applying an algorithm to the plurality of data items, via a computer system having a processor programmed to perform the algorithm, wherein the algorithm runs the plurality of data items against a corresponding filter set in a plurality of filter sets, wherein
• each respective filter set in the plurality of filter sets represents a different hereditary cancer in the plurality of hereditary cancers,
• each respective filter set in the plurality of filter sets includes a respective filter that is configured to be fired at least when the plurality of data items indicates the first human has a familial risk factor for the corresponding hereditary cancer that satisfies a first threshold level of consanguinity,
• each respective filter set in the plurality of filter sets is associated with a corresponding alert in a plurality of alerts, and
• when a respective filter in the corresponding filter set is fired, the first human is deemed to have an actionable risk of the hereditary cancer represented by the corresponding filter set;
• and
• c) communicating a report to the medical professional, via a computer system having a processor programmed to communicate reports, the report comprising the alert associated with each respective filter set in the plurality of filter sets that included a respective filter that was fired in response to applying the algorithm to the plurality of data items of the electronic medical record of the first human.

A computer system for determining whether a first human has an actionable risk for each of a plurality of hereditary cancers, comprising:

• one or more processors;
• memory;
• and
• one or more programs stored in the memory for execution by the one or more processors, the one or more programs comprising instructions for performing a method comprising:
• a) responsive to a request by a medical practitioner, obtaining an electronic medical record associated with the first human, via a computer system having a processor programmed to receive medical records, the electronic medical record of the first human comprising a plurality of data items, wherein the plurality of data items includes:
• an age of the first human,
• whether the first human has been diagnosed with a cancer, and
• an indication of whether a second human has been afflicted with a cancer,
• wherein the second human shares a first degree, second degree, or third degree consanguineous relationship with the first human;
• b) for each respective hereditary cancer in the plurality of hereditary cancers, applying an algorithm to the plurality of data items, via a computer system having a processor programmed to perform the algorithm, wherein the algorithm runs the plurality of data items against a corresponding filter set in a plurality of filter sets, wherein
• each respective filter set in the plurality of filter sets represents a different hereditary cancer in the plurality of hereditary cancers,
• each respective filter set in the plurality of filter sets includes a respective filter that is configured to be fired at least when the plurality of data items indicates the first human has a familial risk factor for the corresponding hereditary cancer that satisfies a first threshold level of consanguinity,
• each respective filter set in the plurality of filter sets is associated with a corresponding alert in a plurality of alerts, and
• when a respective filter in the corresponding filter set is fired, the first human is deemed to have an actionable risk of the hereditary cancer represented by the corresponding filter set;
• and
• c) communicating a report to the medical professional, via a computer system having a processor programmed to communicate reports, the report comprising the alert associated with each respective filter set in the plurality of filter sets that included a respective filter that was fired in response to applying the algorithm to the plurality of data items of the electronic medical record of the first human.