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US 2019/0292534 A1Published application
Modified organisms for improved flavor and aroma
OwnerSean Raspetinventor
Life of this patent
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Abstract
The present disclosure provides for genetically modified organisms that provide numerous health benefits but also have an improved flavor profile and a more palatable aroma for the consumer of the organism.
Claims16
A method of genetic modification of an organism, the method comprising:
- identifying at least one genomic location of the organism,
- wherein the at least one genomic location corresponds to a geosmin synthase gene, a germacradienol synthase gene, MIB synthase gene or 2-MIB synthase gene, 2-pentylfuran synthase gene or 2-pentylfuran producing gene, spermidine synthase gene, spermine synthase gene, theospermine synthase gene, diamine oxidase gene, histamineN-methyltransferase gene, beta-ionone synthase gene, or any combination thereof;
- and
- editing the at least one genomic location of the organism by knocking out or making non-functional at least one genomic location or in the alternative, upregulating or downregulating the at least one genomic location.
1 more element
A method of producing a better tasting organism comprising:
- editing the genome of the organism to target production of at least one of the following molecules:
- geosmin, 2-methylisoborneol, 2-pentylfuran, putrescine, cadaverine, spermine, spermindine, thermospermine, and polyamines having a molecular weight below 350 Daltons.
A method of producing a better tasting organism comprising:
- editing a genome of the organism to target production of at least one of the following molecules:
- Beta-cyclocitral, 1-octen-3-ol, Sulfides (including dimethyl sulfide and dimethyl trisulfide), Thiomethyl esters, and 2,4-decadienal, 1,3-Octadiene, Octatrienes, 4-Methylthio-1,2-dithiolane, 5-Methylthio-1,2,3-trithiane, Dimethyldisulfide, Dimethyltrisulfide, Methyl ethanethiolate, Methyl propanethiolate, Methyl 2-methylpropanethiolate, Methyl 3-methylbutanethiolate, Pentanal, Heptanal, Dimethyltetrasulfide, 1,2,4-Trithiolane, Oct-1-en-3-o-1, Octan-1-ol, Oct-2-en-1-ol, 1-octen-3-one, Octan-3-one, Benzene, Naphthalene, Hexanal, Pentan-3-one, Styrene, Octanal, Decanal, Nonanal, Undecanal, histamine, Thioesters, Uric acids, Uronic acids, Purines, Pinene, Limonene, Borneol, Fenchol, Indole, Skatole, Polyunsaturated fatty acids, and Free fatty acids.
Dependencies are inferred from the claim text.