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US 2019/0292258 A1Published application
Anti-cd47 antibodies
AssigneeAbsos, LLC
InventorsJohn Lippincott, Dana Duey, Larry Green
Life of this patent
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Abstract
The present invention provides anti-CD47 monoclonal antibodies and related compositions, which may be used in any of a variety of therapeutic and diagnostic methods for the treatment of cancer, ischemic-reperfusion injury, and other diseases.
Claims15
An isolated anti-CD47 antibody, or an antigen-binding fragment thereof, comprising:
- i) a heavy chain variable region comprising a VHCDR1 selected from SEQ ID NOs:22-42, a VHCDR2 selected from SEQ ID NOs:43-63, and a VHCDR3 selected from SEQ ID NOs:64-84, respectively, and
- ii) a light chain variable region comprising a VLCDR1 selected from SEQ ID NOs:106-126, a VLCDR2 selected from SEQ ID NOs:127-147, and a VLCDR3 selected from SEQ ID NOs:148-168, respectively.
Dependencies are inferred from the claim text.