Back to results
US 2019/0292244 A1Published application
Composition and method for the diagnosis and treatment of iron-related disorders
AssigneesAbbVie Deutschland GmbH & Co. KG, AbbVie Inc.
InventorsBernhard Mueller, Andreas Popp, Jennifer M. Perez
Life of this patent
Estimating the term…
Abstract
Provided herein are methods of using the antibodies that bind to RGMc to treat and diagnose iron-related disorders.
Claims5
-138. (canceled)
A humanized monoclonal anti-Repulsive Guidance Molecule c (RGMc) antibody that comprises a variable heavy chain region comprising a complementary determining region (CDR)1 with an amino acid sequence set forth in SEQ ID NO:17, a CDR2 with an amino acid sequence set forth in SEQ ID NO:18;
- a CDR3 with an amino acid sequence set forth in SEQ ID NO:19;
- and a variable light chain region comprising a CDR1 with an amino acid sequence set forth in SEQ ID NO:20, a CDR2 with an amino acid sequence set forth in SEQ ID NO:21, and a CDR3 with an amino acid sequence set forth in SEQ ID NO:22.
Dependencies are inferred from the claim text.