Novel heterocyclic systems and pharmaceutical applications thereof

A compound having the following formula:

• wherein:
• is a phenyl ring which may be unsubstituted or substituted with 1, 2, 3, or 4 substituents independently selected from the group consisting of:
• a halogen atom, CN, R3, OR3, SR3, N(R3)2, C(O)R3, C(O)OR3, NR3C(O)R3, C(O)NR3, SO2R3, NR3SO2R3, and SO2N(R3)2;
• R1 is hydrogen or an unsubstituted or substituted alkyl, aryl, or heteroaryl group;
• R2 is selected from the group consisting of:
• C(O)OR3, CN, N(R3)2, C(O)R3, C(O)NR3, SO2R3, SO2N(R3)2, and PO2R3;
• and
• is a 5 or 6 membered aryl or heteroaryl ring that is either unsubstituted or substituted with 1, 2, 3, or 4 substituents independently selected from the group consisting of:
• a halogen atom, CN, R3, OR3, SR3, N(R3)2, C(O)R3, C(O)OR3, NR3C(O)R3, C(O)NR3, SO2R3, NR3SO2R3, and SO2N(R3)2,
• R3 is hydrogen or a substituted group selected from the group consisting of:
• a C1-6 aliphatic group;
• a monocyclic 3-8 membered saturated, partially unsaturated, or aryl ring having 0-4 heteroatoms independently selected from nitrogen, oxygen, or sulfur;
• a bicyclic 8-10 membered saturated, partially unsaturated, or aryl ring having 0-5 heteroatoms independently selected from nitrogen, oxygen, or sulfur;
• or a pharmaceutically acceptable salt thereof.