Cis-gnetin h and trans-gnetin h as therapeutic agents
AssigneeMiddle Tennessee State University
InventorsYing GAO, Elliot ALTMAN, Anthony FARONE, Hyo PARK
Life of this patent
Estimating the term…
Abstract
The cis-isomer and trans-isomers of the plant-derived compound gnetin H are shown have anticancer properties, anti-inflammatory properties, and low toxicity. Therapeutic and prophylactic compositions that contain cis-gnetin H, trans-gnetin H, an derivatives thereof, as well as methods of making and using said compositions, are provided. cis-gnetin H and/or trans-gnetin H can be used in purified form or as a plant extract.
Claims24
A method for treating or preventing a disease, disorder, or condition in a subject, the method comprising:
- administering to the subject a composition comprising an effective amount of cis-gnetin H, wherein the cis-gnetin H is substantially free of trans-gnetin H;
- wherein the disease, disorder, or condition is selected from the group consisting of a cancer, a precancerous condition, a tumor, an inflammation, an inflammatory disease, and an autoimmune disease.
(canceled)
A pharmaceutical composition comprising:
- at least one of cis-gnetin H, trans-gnetin H, or a derivative thereof;
- and
- a pharmaceutically acceptable carrier.
19-31. (canceled)
A kit comprising:
- at least one of cis-gnetin H, trans-gnetin H, or a derivative thereof;
- a pharmaceutically acceptable carrier;
- and
- instructions for use.
33-34. (canceled)
The kit of claim 34 further comprising one or more additional active agents selected from the group consisting of an immunogen, an antigen and an adjuvant.
(canceled)
Dependencies are inferred from the claim text.