Method for obtaining useful data for the differential diagnosis of liver fibrosis
AssigneesFundacion Publica Andaluza Progreso Y Salud, Universidad Pablo De Olavide, Universidad de Sevilla, Servicio Andaluz De Salud, FundacióN PúBlica Andaluza Para La GestióN De La InvestigacióN En Salud De Sevilla
InventorsAna Isabel Rojas Gonzalez, David Cano Gonzalez, Irene Delgado Sainz, Bernat Soria Escoms, Francisco Martin Bermudez, Manuel Romero Gomez
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Abstract
The invention relates to a method for the diagnosis of liver fibrosis, comprising detecting the level of expression of the gene GATA-4, or the quantity of the protein GATA-4, in the isolated biological sample of liver tissue. The invention also relates to a diagnosis kit.
Claims20
Use of the GATA-4 gene, or GATA-4 protein for the differential diagnosis of hepatic fibrosis.
A method for obtaining useful data for differential diagnosis of hepatic fibrosis comprising:
- a. obtain an isolated biological sample comprising cells from an individual, and
- b. detecting the level of expression of the GATA-4 gene, and/or the amount of GATA-4 protein, in the isolated sample of (a), and
- c. comparing the gene expression obtained in step (b) with a reference amount.
A kit or device comprising the elements needed to analyze the expression level of the GATA-4 gene or the amount of GATA-4 protein.
Dependencies are inferred from the claim text.