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US 2019/0169694 A1Published application
Methods and materials for staging and treating skin cancer
AssigneeMayo Foundation for Medical Education and Research
InventorAlexander Meves
Life of this patent
Estimating the term…
Abstract
This document provides methods and materials for staging and treating skin cancer (e.g., metastatic malignant pigmented skin lesions). For example, methods and materials for using an ITLP expression profile and/or models including an ITLP expression profile to stage skin cancer and/or determine treatment options for skin cancer patients are provided.
Claims10
A method for treating a mammal having skin cancer, wherein said method comprises:
- (a) determining a tumor-node-metastasis (TNM) stage of said skin cancer using a TNM staging system,
- (b) determining that said skin cancer is ITLP positive, and
- (c) treating said mammal using a cancer treatment for a stage one greater than said TNM stage.
A method for assessing skin cancer, wherein said method comprises:
- (a) determining the expression levels of ITGB3, TP53, LAMB1, and PLAT in skin cancer cells obtained from a mammal having skin cancer, and
- (b) classifying said skin cancer as being ITLP negative or ITLP positive based on said expression levels.
Dependencies are inferred from the claim text.