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US 2019/0169664 A1Published application
Microbial platform for production of glycosylated compounds
AssigneeUniversity of Georgia Research Foundation, Inc.
InventorsYajun YAN, Yifei WU, Xinxiao SUN, Yuheng LIN
Life of this patent
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Abstract
Host cells are metabolically engineered to consume glucose and glycerol simultaneously, and to divert glucose from catabolic to anabolic pathways without adversely affecting glucose uptake.
Claims28
A genetically engineered microbe comprising:
- at least one metabolic pathway modification that disrupts glucose catabolism;
- and
- at least one metabolic pathway modification that metabolically redirects phosphoenolpyruvate (PEP) for enhanced uptake of glucose.
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Dependencies are inferred from the claim text.