Lactic acid-utilizing bacteria genetically modified to secrete polysaccharide-degrading enzymes
Assignee3Plw Ltd.
InventorsTal SHAPIRA, Amir ORANIM
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Abstract
Lactic acid (LA)-utilizing bacteria are provided, genetically modified to express and optionally secrete polysaccharide-degrading enzymes, such as cellulases, hemicellulases and amylases, and uses thereof. The polysaccharide-degrading enzymes are advantageous for processing organic waste so that the organic waste can be used as a substrate in industrial fermentation processes, particularly industrial production of discrete lactic acid enantiomer(s). Vectors and constructs useful for genetically modifying the LA-utilizing bacteria are also provided.
Claims14
-45. (canceled)
A lactic acid (LA)-utilizing bacterium genetically modified to produce one or more exogenous polysaccharide-degrading enzyme, wherein the one or more exogenous polysaccharide-degrading enzyme comprises a cellulase, a hemicellulase, an amylase or combinations thereof.
A population of lactic-acid (LA)-utilizing bacteria genetically modified to produce a plurality of exogenous polysaccharide-degrading enzymes comprising a cellulase, a hemicellulase, an amylase or combinations thereof, wherein the population comprises a plurality of sub-populations of LA-utilizing bacteria, each sub-population being genetically modified to produce a different polysaccharide-degrading enzyme.
Dependencies are inferred from the claim text.