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US 2019/0169173 A1Published application
New crystalline form of n-[5-(3,5-difluoro-benzyl)-1h-indazol-3-yl]-4-(4-methyl-piperazin-1-yl)-2-(tetrahydro-pyran-4-ylamino)-benzamide
AssigneeNerviano Medical Sciences S.R.L.
InventorsIlaria CANDIANI, Giovanni OTTAIANO, Attilio TOMASI
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Abstract
The present invention relates to a new crystalline form of N-[5-(3,5-difluoro-benzyl)-1H-indazol-3-yl]-4-(4-methyl-piperazin-1-yl)-2-(tetrahydro-pyran-4-ylamino)-benzamide, process for its preparation, its utility in treating diseases caused by deregulated protein kinase activity and pharmaceutical compositions containing it.
Claims14
1-18. (canceled)
Crystalline Form 4 of N-[5-(3,5-difluoro-benzyl)-1H-indazol-3-yl]-4-(4-methyl-piperazin-1-yl)-2-(tetrahydro-pyran-4-ylamino)-benzamide of the following formula (I)
- wherein said crystalline form is characterized by an X-ray powder diffraction pattern comprising a peak at a 2-theta value of about 8.6±0.2 degrees.
Dependencies are inferred from the claim text.