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US 2019/0169148 A1Published application
Method for treating pain or associated condition or symptom
AssigneeYissum Research Development Company of the Hebrew University of Jerusalem
InventorsRuth Gallily, Raphael Mechoulam, Aviva Breuer
Life of this patent
Estimating the term…
Abstract
Compositions that include certain phenyl substituted cyclohexenyl compounds are administered to a subject in a method for treating obesity or an associated disease or disorder or in a method of reducing food consumption or body weight.
Claims20
A method for treating pain or a condition or symptom associated therewith in a subject in need thereof, said method comprising administering to said subject a therapeutically effective amount of a compound of the general formula (I):
- or a salt, enantiomer, diastereomer, or mixture thereof,
- wherein
- R1, R2 and R3 are each independently a (C1-C10)alkyl, (C2-C10)alkenyl or (C2-C10) alkynyl, optionally substituted by at least one substituent each independently selected from the group consisting of hydroxy and halogen;
- R4 is a (C1-C10)alkyl, (C2-C10)alkenyl or (C2-C10)alkynyl, substituted by at least one substituent of general formula (II):
- X is selected from the group consisting of N, N+H, N+(C1-C10 alkyl), O+, S+, P, and P+H;
- and
- R5 and R6 are each independently selected from the group consisting of H, (C1-C10) alkyl, (C2-C10)alkenyl, and (C2-C10)alkynyl, or both R4 and R6 together with X may form a (C3-C8)heterocyclic ring, wherein R5 and R6 each independently is optionally interrupted by at least one group each independently selected from the group consisting of —O—, —NH—, N+(C1-C10 alkyl), and —S—.
4 more elements
Dependencies are inferred from the claim text.