Filtration assembly and filtration system including the same

A tangential flow filtration system comprising:

• a plurality of tangential flow filtration assemblies;
• and
• at least one conduit fluidly connecting one of the plurality of tangential flow filtration assemblies to a subsequent assembly of the plurality of tangential flow filtration assemblies, the system comprising n-1 conduits, wherein n is the number of tangential low filtration assemblies in the plurality of tangential flow filtration assemblies, and
• wherein each tangential flow filtration assembly comprises:
• a first winding tangential flow channel comprising an inlet at an endpoint of the first tangential flow channel and an outlet at an opposite endpoint of the first tangential flow channel, the first winding tangential flow channel further comprising a first cross-sectional area at the inlet and a second cross-sectional area at the outlet;
• a second winding tangential flow channel comprising an inlet at an endpoint of the second tangential flow channel and an outlet at an opposite endpoint of the second tangential flow channel the second winding tangential flow channel further comprising a first cross-sectional area at the inlet and a second cross-sectional area at the outlet;
• and
• a filtration membrane positioned between the first and second tangential flow channels,
• wherein the first cross-sectional area of the first tangential flow channel is greater than the second cross-sectional area of the first tangential flow channel, and
• wherein the first cross-sectional area of the second tangential flow channels is less than the second cross-sectional area of the second tangential flow channel.