Contactless electropermeabilization electrode and method
AssigneeVGX Pharmaceuticals, Inc.
InventorsThomas Joseph KARDOS, Stephen Vincent KEMMERRER, Rune KJEKEN, Kate BRODERICK, Jay MCCOY, Michael P. FONS
Life of this patent
Estimating the term…
Abstract
Devices and methods for delivering an electropermeabilizing pulse of electric energy to a tissue surface to enable delivery into cells in the tissue therapeutic substances. The device incorporates a source capable of generating a sufficient voltage potential to deliver a spark across a gap and delivers same to the tissue surface.
Claims13
A method of enabling the delivery of therapeutic substances into cells of tissue of a mammal by using a spark electropermeabilizing device to deliver an electropermeabilizing electric voltage potential to the surface of a mammalian tissue, comprising:
- generating a voltage potential sufficient to jump a gap of predetermined distance;
- delivering said generated voltage potential in the form of a spark that can jump said gap to the surface of the mammalian tissue without causing macroscopic damage to an integrity of the surface of the mammalian tissue;
- and
- delivering the therapeutic substances to cells within the mammalian tissue.
Dependencies are inferred from the claim text.