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US 2019/0167854 A1Published application
Drug coated balloon catheters for nonvascular strictures
AssigneeUrotronic, Inc.
InventorLixiao Wang
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Abstract
Embodiments of the present invention provide a method for treatment of nonvascular body lumen strictures such as benign prostatic hyperplasia (BPH), urethral strictures, ureteral strictures, prostate cancer, esophageal strictures, sinus strictures, biliary tract strictures, asthma and chronic obstructive pulmonary disease (COPD). The method involves delivering, preferably via drug coated balloon catheters, of anti-inflammatory and anti-proliferative drugs (rapamycin or paclitaxel and their analogues) and one or more additives.
Claims22
A method for treating sinusitis, a sinus stricture, or a nasal lumen, the method comprising:
- inserting a balloon catheter into a target site, wherein the target site is the sinus stricture or the nasal lumen, the balloon catheter comprising
- a coating layer overlying an exterior surface of a balloon that is inflatably expandable, the coating layer comprising
- an initial drug load comprising mometasone furoate, wherein the initial drug load has a density of the mometasone furoate in the coating layer of 1 to 20 μg per mm2 of the exterior surface of the balloon, and
- an additive;
- inflating the balloon at least until the coating layer contacts walls of the target site to transfer at least some of the coating layer to the walls of the target site;
- deflating the balloon;
- and
- withdrawing the balloon catheter from the target site.
5 more elements
Dependencies are inferred from the claim text.