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AssigneesAcademisch Ziekenhuis Leiden, Xeltis AG, Universiteit Maastricht
InventorsJoris Ivo Rotmans, Tonia Caroline Rothuizen, Lorenzo Moroni, Clemens Antoni Van Blitterswijk, Febriyani Fiain Rochel Damanik, Tom Lavrijsen, Martijn Antonius Johannes Cox, Antonius Johannes Rabelink
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The present disclosure relates to in situ tissue engineering, more specifically in situ vascular tissue engineering with the aim of providing a tissue structure which can be used e.g. as a substitute blood vessel or as a blood vessel functioning as cannulation site in hemodialysis. In particular, the disclosure involves tissue structure formation around a subcutaneously implanted synthetic rod. In addition, the disclosure involves a method for producing said synthetic rod.
A device configured to provide for a tissue structure by eliciting a foreign body response, wherein the device comprises a polymer capable of eliciting a foreign body response, wherein a surface of the device has a root mean square roughness (Rq) of at least 100 nm, and wherein the device is not at least partially in a form of a rod.
A method for providing a tissue structure, wherein the method comprises the steps of:
Dependencies are inferred from the claim text.